The .460 Weatherby was a 500 grain FMJ at 2700 fps...and felt it...noticeably more recoil than the .500 Nitro, plus the rifle was a pound or two lighter.
I shot a .577 nitro express out of a double rifle. 560 gn bullet going 1990 fps by my chrony. I shot one, once and unless charged by a elephant will never again