A 50 yd zero is more precise, you know exactly where your round will strike out to the longest practical distance you will use the pistol. It is a habit I developed during the early days of IPSC competition where you would routinely shoot standard exercises out to 50 yds. In those days my practice routine included 50 yd head shots on an IPSC (now USPSA) target. I don't notice much drop , if any out to 50 yds using 125 gr 9mm bullets at 1000 fps.
I remember one match at the Wesfield range that included a rifle side match with targets at 10, 25, 50, 75 and 100yds. I entered it with my .45 as a warm up for the main IPSC match. The targets weren't pretty, but I managed to put all of my rounds on paper. There is no secret to long range shooting with a pistol as long as you have decent ammo and the gun is zeroed properly.
I remember one match at the Wesfield range that included a rifle side match with targets at 10, 25, 50, 75 and 100yds. I entered it with my .45 as a warm up for the main IPSC match. The targets weren't pretty, but I managed to put all of my rounds on paper. There is no secret to long range shooting with a pistol as long as you have decent ammo and the gun is zeroed properly.