My advice to you is try before you buy, either at a shoot with people here or up at a rental range like Manchester. Especially when it comes to pistols, some will feel good in your hand and others will be a weird angle, too big, etc... It's a very personal thing.
Either start with .22 or if you really want large calibers right off the bat do yourself a favor and get a full sized heavy pistol to absorb the recoil.
Either start with .22 or if you really want large calibers right off the bat do yourself a favor and get a full sized heavy pistol to absorb the recoil.